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blog:bpaddock:epigenetics_why_women_are_stripey [2014/07/13 15:59] (current)
bpaddock Created Epigenetics: Why Women Are Stripey
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 +====== Epigenetics Why Women Are Stripey ======
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 +<WRAP centeralign>​
 +{{youtube>​BD6h-wDj7bw}}
 +</​WRAP>​
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 +<​blockquote>​
 +Epigenetics means women have different active x-chromosomes in different cells.
 +
 +When a female embryo is four days old it consists of just 100 cells. At this point the x-chromosome from Mom and the one from Dad are both active. But in order for proper development to occur, one of the x chromosomes must be switched off.
 +
 +Through a tiny molecular battle within each cell, one of the x-chromosomes wins and remains active while the loser is deactivated.
 +
 +This is done by wrapping the DNA tighter around proteins, modifying histone tails, and DNA methylation - molecular markers to indicate this DNA should not be read.
 +
 +What's surprising is that it's pretty random which x chromosome wins - sometimes it's Mom's and sometimes it's Dad's. So when a female is just 100 cells big, her cells have a mix of active x-chromosomes,​ some from Mom and some from Dad.
 +</​blockquote>​
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 +{{tag>​Epigenetics chromosomes dna rna female}}
 +
 +
 +~~DISCUSSION~~